How Long Does a Toradol Injection Last? Pain Relief Duration, Benefits, and Precautions
- Infusion Oasis
- Aug 4
- 2 min read
Toradol, the brand name for ketorolac tromethamine, is a powerful nonsteroidal anti-inflammatory drug (NSAID) used to manage moderate to severe acute pain. Commonly used after surgeries or injuries, it provides relief without the sedating effects of opioids. Understanding how long a Toradol injection lasts and its dosing guidelines helps patients make informed decisions about pain management.
Duration of Pain Relief
On average, a Toradol injection provides pain relief for about 4 to 6 hours, making it effective for managing moderately severe acute pain after surgeries or injuries. It has a rapid onset, usually within 30 minutes, and can be administered either intravenously (IV) or intramuscularly (IM). Due to its potency and potential side effects, Toradol use is limited to short-term use, no longer than 5 days.

Dosage Guidelines
For adults receiving a Toradol injection, typical dosages range from 30 mg to 60 mg. Here’s how it usually breaks down:
Intravenous (IV):
30 mg once
Patients 65 years or older, renally impaired, or under 110 lb: 15 mg once
Intramuscular (IM):
30 or 60 mg once
Patients 65 years or older, renally impaired, or under 110 llb: 30 mg once
Multiple-dose treatment administered every 6 hours:
30 mg IV or IM every 6 hours, not exceeding 120 mg per day
Patients 65 years or older, renally impaired, or under 110 lb: 15 mg IV or IM every 6 hours, not exceeding 60 mg per day
Oral dosing:
Only recommended as continuation therapy after IV or IM dosing and should not be used as an initial dose. The usual oral dose is 20 mg once, followed by 10 mg every 4 to 6 hours, not to exceed 40 mg per day.
It's essential to limit doses to every 6 hours, ensuring the total daily dosage does not exceed 120 mg. Always begin with IV or IM dosing; oral use is only recommended as a continuation if needed. Regarding safety, Toradol is intended for short-term use and should not go beyond 5 days (oral included). Increasing the dose does not improve effectiveness and may raise the risk of serious side effects.
Precautions to Consider
While Toradol can be a powerful pain reliever, certain precautions must be observed to ensure patient safety. It is not suitable for individuals who have:
Active or recent gastrointestinal bleeding or peptic ulcer disease
History of asthma, urticaria, or allergic reactions to aspirin or NSAIDs
Coronary artery bypass graft surgery
Suspected or confirmed bleeding disorders
Concurrent use of aspirin, NSAIDs, probenecid, or pentoxifylline
Pregnancy or Breastfeeding
Informing the healthcare provider about all existing conditions and medications is crucial to prevent any potential complications.
Advantages of Toradol
Non-Opioid Relief: Ketorolac relieves pain effectively without the risks of dependence or sedation seen with opioids.
Rapid Onset: Patients can expect pain relief typically within 30 minutes of injection.
Final Thoughts
A Toradol injection provides strong pain relief lasting approximately 4 to 6 hours. While it is an effective option for managing moderate to severe pain, proper dosing and awareness of precautions are essential to ensure safe and appropriate use.
If you're experiencing significant pain, consult a healthcare provider to determine whether Toradol is a suitable treatment option.